Name | HexanitrodiphenylaMine |
Synonyms | HNDP HNDPH CI 10360 AURANTIA DIPICRYLAMINE LABOTEST-BB LT00000320 HexanitrodiphenylaMine HEXANITRODIPHENYLAMINE Dipicrylamine ammonium salt |
CAS | 131-73-7 |
EINECS | 205-037-8 |
Molecular Formula | C12H5N7O12 |
Molar Mass | 439.21 |
Density | 1.6613 (rough estimate) |
Melting Point | about 238° with dec |
Boling Point | 550.83°C (rough estimate) |
Water Solubility | 60mg/L(17 ºC) |
pKa | pK1:5.42(+1) (25°C) |
Refractive Index | 1.6400 (estimate) |
Risk Codes | R2 - Risk of explosion by shock, friction, fire or other sources of ignition R26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed. R33 - Danger of cumulative effects R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
Safety Description | S35 - This material and its container must be disposed of in a safe way. S36 - Wear suitable protective clothing. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
UN IDs | 0079 |
Hazard Class | 1.1D |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
Introduction | chlorpheniramine, chlorpheniramine, chlorpheniramine, chlorpheniramine, chlorpheniramine, cloromiprone, maleamine and Triton) antagonized H. Receptors, against the allergic effect of histamine; The drug does not affect the metabolism of histamine and does not prevent the release of histamine in the body. At the same time, it has anti-M choline receptor and central inhibitory effect. General sedative effect is weak, mainly for a variety of allergic diseases, can also be combined with other Chinese and Western medicine in the treatment of colds. |
pharmacological action | Chlorpheniramine is the first generation antihistamine, which has strong competitive blocking histamine H on allergic target cells. The role of the receptor. Therefore, it has better anti-allergic effect. It has certain central inhibitory effect and anticholinergic effect. But compared with other types of traditional antihistamines is light, so after taking the drowsiness, dry mouth, constipation, sputum thickening and other reactions lighter. Before the advent of the new generation of antihistamines, antihistamines were the most widely used in clinical practice. |
indications | for skin and mucosa allergic diseases and acute and chronic urticaria, angioedema, perennial allergic rhinitis, seasonal Rhinitis, allergic conjunctivitis, insect stinging dermatitis, contact dermatitis, etc. More for children with allergic diseases, for Upper Respiratory Infections of children, gastrointestinal allergy symptoms are often effective. Can also be used to prevent transfusion reactions and drug allergy. |
side effects | 1. Sometimes there are mild dry mouth, dizziness, Nausea and other reactions, drowsiness is mild. 2. The dosage of roughly acute poisoning, adults often appear central inhibition. When children are poisoned, they are usually excited centrally. When Respiratory Insufficiency, the use of artificial respiration, oxygen and other supportive therapy, the use of central stimulants. If necessary, the upper adrenal gland gland can be used to maintain blood pressure intravenous infusion of adenosine, but not with epinephrine. Histamine injection should not be used as an antidote in the rescue. |
category | explosive articles |
toxicity grade | poisoning |
Acute toxicity | oral-rat LD: >500 mg/kg |
explosive hazard characteristics | high heat, vibration, impact, and friction burst |
flammability hazard characteristics | toxic NOx smoke from combustion |
storage and transportation characteristics | light weight; Warehouse ventilation, away from open flame, high temperature, sunlight; And oxidant, separate storage of combustible materials |
extinguishing agent | Water |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |